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Table 3 Primary and secondary outcomes

From: Laparoscopic versus open appendectomy in patients with suspected appendicitis: a systematic review of meta-analyses of randomised controlled trials

 

Golub 1998

Meynaud-Kraemer 1999

Temple 1999

Bennett 2007

Li 2010

Liu 2010

Sauerland 2010

Wei 2011

Ohtani 2012

Primary outcomes

         

pain on postoperative day 1 [WMD, 95%-CI]

-

-

-

LA (5) [-0.8, -1.84;0.25]

LA* (8) [-0,7, -1.22;-0.19]

-

LA* (15) [-0.82, -1.14;-0.49]

-

-

wound infections [OR, 95%-CI]

LA* (16) [0.3, 0.19;0.47]†

LA* (8) [0.33, 0.18;0.61]†

LA* (10) [0.4, 0.24;0.69]†

LA* (25) [0.52, 0.39;0.70]

LA* (31) [0.45, 0.34;0.59]†

LA* (13) [0.51, 0.36;0.73]†

LA* (50) [0.43, 0.34;0.54]†

LA* (20) [-, 0.3;0.56]†

LA* (32) [0.46, 0.34;0.62]†

intraabdominal abscesses [OR, 95%-CI]

OA (15) [2.2, 0.88;6.64]†

-

OA (6) [1.94, 0.68;5.58]†

OA* (25) [2.29, 1.48;3.53]†

OA* (17) [1.56, 1.01;2.43]†

-

OA* (45) [1.87, 1.19;2.93]†

OA (12) [-, 0.93;2.14]†

-

mortality

-

-

-

-

-

LA (7)

-

-

-

[OR, 95%-CI]

     

[0.97, 0.29;3.25]†

   

secondary outcomes

         

duration of surgery [WMD, 95%-CI]

OA* (16) [18.3, -;-]

-

OA* (8) [18.1, 12.87;23.15]

OA* (22) [14.61, 9.04;20.19]

OA* (36) [12.35, 7.99;16.72]

OA* (8) [7.6, 6.03;9.17]

OA* (38) [10,24 5.51;14.97]

OA* (25) [10.71, 6.76;14.66]

OA* (36) [13.12, 9.72;16.51]

overall conversion rate {range}

9.7% (14) {0%-20%}

-

11% (-) {5%-20%}

-

-

-

-

-

-

length of hospital stay [WMD, 95%-CI]

LA* (14) [-0,61, -;-]

-

LA (8) [-0.16, -0.44;0.15]†

LA* (18) [-0.62, -1.05;-0.18]

LA* (32) [-0.6, -0.85;-0.36]

LA* (8) [-0.82, -0.93;-0.7]

LA* (34) [-1.13, -1.51;-0.74]

LA* (23) [-0.68, -1.02;-0.35]

LA* (33) [-0.79, -1.06;-0.52]

in-hospital costs (including surgery costs) [OR, 95%-CI]

-

-

-

-

-

-

OA* (6) [1.32, 0.42;2.22]

-

OA (7) [-]

time until return to work [WMD, 95%-CI]

-

-

-

-

-

-

LA (8) [-1.6, -5.22;2.02]

LA* (11) [-3.09, -5.22;-0.97]

LA* (10) [-3.18, -5.09;-1.27]

  1. LA, in favour for laparoscopic appendectomy; (n), number of studies included for analysis; OA, in favour for open appendectomy; OR, Odds ratio; WMD, weighted mean differences; -, not reported; *direction of effect statistically significant (p ≤ 0.05); homogeneous effect size.