Liver regeneration as evaluated by [ 3
H]-thymidine incorporation into hepatic DNA in 60-70% partially hepatectomized rats and SB-258719. Time course of liver regeneration as evaluated by [3H]-thymidine incorporation into DNA in 60-70% partially hepatectomized rats having received SB-258719 (4 mg/kg bodyweight) 16 h after partial hepatectomy. Results represent the findings from at least five rats killed at 18, 20, 24, 32, 40, 48, 60 and 72 h (group E). Values are expressed as means ± SE.