Table 1 Laennec scoring system for staging fibrosis in liver specimens
Stage | Name | Septa (thickness and number) | Criteria | Score |
|---|---|---|---|---|
0 | No definite fibrosis | Â | Â | 0 |
1 | Minimal fibrosis | +/- | No septa or rare thin septum; may have portal expansion or mild sinusoidal fibrosis | 1 |
2 | Mild fibrosis | + | Occasional thin septa; may have portal expansion or mild sinusoidal fibrosis | 2 |
3 | Moderate fibrosis | ++ | Moderate thin septa; up to incomplete cirrhosis | 3 |
4A | Mild, definite, or probable cirrhosis | +++ | Marked septation with rounded contours or visible nodules. Most septa are thin (one broad septum allowed) | 4 |
4B | Moderate cirrhosis | ++++ | At least two broad septa, but not very broad septa and less than half of biopsy length composed of minute nodules | 5 |
4C | Severe cirrhosis | +++++ | At least one very broad septum or more than half of biopsy length composed of minute nodules (micronodular cirrhosis) | 6 |