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Table 3 Overall and age- and sex-specific incidence densities and relative hazard of gallstone in the osteoporosis and comparison cohorts

From: Osteoporosis increases subsequent risk of gallstone: a nationwide population-based cohort study in Taiwan

Factor Osteoporotic group Comparative group Crude HR Adjust HR
Incident cases Person-years ID 1 95% CI Incident cases Person-years ID 1 95% CI   
Age (y)a           
50-64 42 3080.05 13.64 9.54 - 17.73 103 12702.40 8.11 6.55 - 9.67 1.68 (1.17 - 2.40)** 1.56 (1.06 - 2.28)*
65-79 60 3846.65 15.60 11.68 - 19.51 170 15720.01 10.81 9.20 - 12.43 1.44 (1.07 - 1.94)* 1.25 (0.92 - 1.71)
≥ 80 12 868.91 13.81 6.05 - 21.57 38 3544.48 10.72 7.33 - 14.11 1.28 (0.67 - 2.46) 1.31 (0.64 - 2.68)
Sexb           
Men 17 1142.92 14.87 7.86 - 21.89 48 4719.56 10.17 7.31 - 13.03 1.46 (0.84 - 2.54) 1.09 (0.60 - 1.96)
Women 97 6652.69 14.58 11.70 - 17.46 263 27247.33 9.65 8.49 - 10.81 1.51 (1.20 - 1.91)** 1.40 (1.09 - 1.79)**
Total 114 7795.61 14.62 11.96 - 17.29 311 31966.89 9.73 8.65 - 10.80 1.50 (1.21 - 1.86)*** 1.35 (1.07 - 1.69)*
  1. *p <0.05,**p <0.01, ***p <0.001.
  2. HR, hazard ratio; ID, incidence density (per 1000 patient-years); CI, confidence interval.
  3. 1Based on the Poisson assumption.
  4. aAdjusted for sex, age, monthly income, region, urbanization level, hypertension, hyperlipidemia, diabetes, cirrhosis, spinal cord injury, hormone replacement, and clofibrate.
  5. bAdjusted for age, monthly income, region, urbanization level, hypertension, hyperlipidemia, diabetes, cirrhosis, spinal cord injury, hormone replacement, and clofibrate.