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Table 1 Mortality rates in cases of upper gastrointestinal bleed or perforation according to date of publication and size of study, for all cases and those taking NSAID

From: Mortality with upper gastrointestinal bleeding and perforation: effects of time and NSAID use

  All Cases Cases using NSAIDs
  Number of   Number of  
Analysis Cases Deaths Mortality (%; 95% CI) Cases Deaths Mortality (%; 95% CI)
Overall 61067 5001 8.2 (8.0 to 8.4) 5526 904 16.4 (15.4 to 17.3)
By date of publication       
Before 1997 [1] 11361 1319 11.6 (11.0 to 12.2) 4046 595 14.7 (13.6 to 15.8)
Between 1997 and 2008 49706 3682 7.4 (7.2 to 7.6) 1480 309 20.9 (18.8 to 22.9)
By number of cases       
≥ 2000 35058 2410 6.9 (6.6 to 7.1) 3443 576 16.7 15.5 to 18.0)
200–1999 23147 2345 10.1 (9.7 to 10.5) 1465 297 20.3 (18.2 to 22.3)
1–199 2862 246 8.6 (7.6 to 9.6) 618 31 5.0 (3.3 to 6.7)