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Table 2 Effects of fluvoxamine (FLU) alone and ranitidine (RAN) alone on tGSH, NO, MPO, and MDA levels in the stomach tissues of rats.

From: Antiulcer activity of fluvoxamine in rats and its effect on oxidant and antioxidant parameters in stomach tissue

Drugs Dose
(mg/kg)
tGSH MDA NO MPO
FLU 25 14.9 ± 0.6 2.1 ± 0.3 80.4 ± 6.3 1.0 ± 0.02
FLU 50 15.1 ± 0.3* 1.8 ± 0.2* 95.2 ± 4.5* 0.8 ± 0.04*
FLU 100 17.1 ± 0.8* 1.7 ± 0.3* 99.7 ± 5.7* 0.5 ± 0.03*
FLU 200 18.3 ± 0.6* 1.6 ± 0.2* 105.1 ± 5.2* 0.4 ± 0.01*
RAN 50 15.8 ± 0.4* 2.1 ± 0.5* 96.8 ± 4.7* 0.6 ± 0.03*
Intact (Control) - 12.7 ± 0.2 2.3 ± 0.4 83.4 ± 3.6 1.1 ± 0.05
  1. *Significant at p < 0.05 when compared to intact control.