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Table 1 Effects of high rHu-EPO concentrations on Bcl-2 mRNA levels in rat hepatocytes

From: No evidence for protective erythropoietin alpha signalling in rat hepatocytes

Treatment Normoxia Hypoxia (3% O 2 )
Control 0.11 ± 0.03 fg/μl 0.05 ± 0.02 fg/μl
EPO 50 U/ml 0.09 ± 0.03 fg/μl 0.04 ± 0.01 fg/μl
EPO 100 U/ml 0.08 ± 0.03 fg/μl 0.04 ± 0.02 fg/μl
  1. NOTE. Quantitative (RT-)PCR from total RNA was performed as described in Methods after a 24 hours incubation of cultured rat hepatocytes with or without high doses of rHu-EPO under normoxia or hypoxia (3% O2). Data are the means ± SD of 4 separate experiments with hepatocytes different animals each.