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Table 3 The expression of GATA-4 and GATA-6 in different cell types of the gastrointestinal mucosa on the basis of conventional and double immunohistochemistry

From: Transcription factors GATA-4 and GATA-6 in normal and neoplastic human gastrointestinal mucosa

Tissue Cell type GATA-4 GATA-6
Stomach    
Corpus    
  Surface epithelial cells ++ ++
  Neck cells +++ ++
  Parietal cells +++ ++
  Neuroendocrine cells - -
Antrum    
  Surface epithelial cells ++ +
  Neck cells +++ ++
  Glandular cells ++ +++
  Neuroendocrine cells - -
Duodenum    
  Villus enterocytes +++ ++
  Crypt enterocytes ++ +++
  Neuroendocrine cells - -
  Goblet cells - +
  Paneth cells - ++
Colon    
  Surface colonocytes - +
  Crypt cells - +++
  Goblet cells - ++
  Neuroendocrine cells - -
  1. The expression patterns based on the number of positive cells detected:
  2. - no expression,
  3. + low expression; <20% of the cells positive
  4. ++ moderate expression; 20–60% of the cells positive
  5. +++ abundant expression; >60% of the cells positive