Relation between Plasma PTX3 levels and fibrosis stage. Comparison between plasma PTX3 levels in various stages of fibrosis. Box plots of plasma PTX3 levels showing interquartile range (box), median (thick line), range (thin lines) and outliers (circles). The length of the box represents the interquatile range within which 50% of the values were located. A steady stepwise increase in serum high-sensitivity CRP levels was observed with increasing severity of hepatic fibrosis (p = 0.0049).