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Table 3 Results of testing for differences in SNP rs2290602 frequency between NAFLD group and control group, NASH group and contol group, NASH group and simple steatosis group.

From: Association between PPARGC1A polymorphisms and the occurrence of nonalcoholic fatty liver disease (NAFLD)

 

NAFLD

Control

Allele frequency mode

Recessive mode

Dominant mode

Study

11

12

22

11

12

22

χ2

P-value

Odds ratio (95% CI)

χ2

P-value

Odds ratio (95% CI)

χ2

P-value

Odds ratio (95% CI)

NAFLD vs. Control

34

67

13

99

222

113

1.6

0.00363

1.55 (1.15 – 2.08)

2.4

0.12008

1.44 (0.91 – 2.28)

10.9

0.00095

2.73 (1.48 – 5.06)

NASH vs. Control

24

34

6

99

222

113

1.0

0.00093

1.90 (1.29 – 2.79)

6.5

0.01097

2.03 (1.17 – 3.53)

8.5

0.00352

3.40 (1.43 – 8.10)

NASH vs. simple steatosis

24

34

6

10

33

7

2.8

0.09168

1.58 (0.93 – 2.69)

4.1

0.04270

2.40 (1.02 – 5.66)

0.6

0.44076

1.57 (0.49 – 5.02)