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Table 1 Transformation of T51B cells by MNNG and FAC1.

From: Neoplastic transformation of rat liver epithelial cells is enhanced by non-transferrin-bound iron

MNNG FAC Number of colonies per 25,000 cells
0 0 0.0 (+/- 0.0)
0.5 0 1.3 (+/- 0.8)
0 20 μM 1.5 (+/- 0.5)
0.5 20 μM 4.3 (+/- 1.0)
0 50 μM 1.8* (+/- 0.2)
0.5 50 μM 17.5 (+/- 3.3)
0 200 μM 1.8 (+/- 1.4)
0.5 200 μM 21.5* (+/- 2.1)
0 500 μM 3.0 (+/- 1.4)
0.5 500 μM 5.3 (+/- 1.3)
  1. 1 Cells exposed or not to 0.5 μg/ml MNNG were cultured in FAC for 12 weeks (6 passages) prior to soft agar assay: means of n = 4 dishes (+/- s.e.m); *p < 0.01 compared to untreated cells.