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Table 3 Cost* and other data summarized

From: An economic model of long-term use of celecoxib in patients with osteoarthritis

 

Base case (range)

Reference

Celecoxib 200 mg/d

$2.64 ($2.11–$3.17)

http://drugstore.com

Naproxen 1000 mg/d

$0.45 ($0.36–$0.54)

http://drugstore.com

Diclofenac 100 mg/d

$0.64 ($0.51–$0.77)

http://drugstore.com

Omeprazole (over-the-counter) 20 mg/d

$0.60 ($0.48–$0.72)

http://drugstore.com

Price reduction generic celecoxib

55% (30%–80%)

[61,63]

POB inpatient-hospital plus physician (ALOS = 5.56 days)

$12,796 ($10,234–$15,355)

[12,40]

POB outpatient-hospital plus physician

$1,813 ($1,450–$2,176)

[12,160,161]

Peptic ulcer inpatient-hospital plus physician (ALOS = 4.10 days)

$7,353 ($5,882–$8,824)

[12,40]

Peptic ulcer outpatient discrete event including endoscopy

$1,554 ($1,243–$1,865)

[12,160,161]

Dyspepsia outpatient initial event including endoscopy

$1,208 ($966–$1,450)

[12,160,161]

Ongoing annual medical and laboratory costs chronic peptic ulcer or dyspepsia

$130 ($104–$156)

[160], Estimates RBRVS

POB proportion of surgery DRGs

14.2%

[40]

POB admissions through emergency

89.7%

[40]

Proportion of peptic ulcer patients admitted to hospital

4.37%

[40]

Discount rate for costs and QALYs

3.0%

 

Price inflation rate

2.0%

 
  1. POB, perforation, obstruction, bleeding ulcer; ALOS, average length of stay; RBRVS, resource-based relative value scale; DRGs, diagnosis-related groups. *Drug prices as of February 2006.