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Table 3 Cost* and other data summarized

From: An economic model of long-term use of celecoxib in patients with osteoarthritis

  Base case (range) Reference
Celecoxib 200 mg/d $2.64 ($2.11–$3.17) http://drugstore.com
Naproxen 1000 mg/d $0.45 ($0.36–$0.54) http://drugstore.com
Diclofenac 100 mg/d $0.64 ($0.51–$0.77) http://drugstore.com
Omeprazole (over-the-counter) 20 mg/d $0.60 ($0.48–$0.72) http://drugstore.com
Price reduction generic celecoxib 55% (30%–80%) [61,63]
POB inpatient-hospital plus physician (ALOS = 5.56 days) $12,796 ($10,234–$15,355) [12,40]
POB outpatient-hospital plus physician $1,813 ($1,450–$2,176) [12,160,161]
Peptic ulcer inpatient-hospital plus physician (ALOS = 4.10 days) $7,353 ($5,882–$8,824) [12,40]
Peptic ulcer outpatient discrete event including endoscopy $1,554 ($1,243–$1,865) [12,160,161]
Dyspepsia outpatient initial event including endoscopy $1,208 ($966–$1,450) [12,160,161]
Ongoing annual medical and laboratory costs chronic peptic ulcer or dyspepsia $130 ($104–$156) [160], Estimates RBRVS
POB proportion of surgery DRGs 14.2% [40]
POB admissions through emergency 89.7% [40]
Proportion of peptic ulcer patients admitted to hospital 4.37% [40]
Discount rate for costs and QALYs 3.0%  
Price inflation rate 2.0%  
  1. POB, perforation, obstruction, bleeding ulcer; ALOS, average length of stay; RBRVS, resource-based relative value scale; DRGs, diagnosis-related groups. *Drug prices as of February 2006.