Quantitation of Reg3α protein in wild type and CF mice during acute pancreatitis. Pancreatic homogenates were used to measure Reg3α tissue content by ELISA. Values were normalized to total protein content of the homogenates. Control mice were untreated or injected with 0.9% NaCl. Mice for the 1 h time point received a single injection of caerulein and were sacrificed one hour after injection. The other data are from mice that received 7 hourly caerulein injections and the times are relative to the first injection. Values are presented on a semi-log plot as means and sem. (*) p < 0.05 compared to control of the same genotype. (+) p < 0.05 comparing CF to wild type at the same time point. n = 3 to 7 mice per group and time point.