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Table 2 Number (× 106 cells) of hepatic mononuclear cells 14 days after RRV challenge

From: Loss of interleukin-12 modifies the pro-inflammatory response but does not prevent duct obstruction in experimental biliary atresia

Genotype

Injection

CD3/CD4+

CD3/CD8+

Neutrophils

IL-12KO

Saline

0.26 ± 0.1

0.14 ± 0.03

0.39 ± 0.2

IL-12KO

RRV

0.56 ± 0.1*

0.50 ± 0.2*

1.80 ± 0.01*@

Wild-type

RRV

0.70 ± 0.03*

0.56 ± 0.2*

1.0 ± 0.2*

  1. *P < 0.01 when compared to IL-12KO mice treated with saline.
  2. @P < 0.05 when IL-12KO mice treated with RRV are compared to wild-type mice also treated with RRV.
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BMC Gastroenterology

ISSN: 1471-230X

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