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Table 3 Correlation between BMD and serum cytokines, and biochemical markers in children with chronic hepatitis C treated with IFN-alpha.

From: Bone mineral density and cytokine levels during interferon therapy in children with chronic hepatitis B: does interferon therapy prevent from osteoporosis?

IL-1β

.501**

            

IL-2r

.075

.096

           

IL-6

.167

-.101

-.163

          

IL-8

.137

.251

.248

-.126

         

PTH

.005

-.012

.009

.121

.088

        

s-CTX

-.087

-.253

.140

-.060

.372**

-.155

       

ALP

-.013

-.049

-.055

-.092

.361**

-.102

.179

      

Osteocalcin

.105

-.355**

.016

.135

-.205

-.101

.256

-.006

     

ALT

.189

.494**

.087

-.161

.243

.122

-.257

.251

-.206

    

AST

.214

.528**

.125

-.192

.253

.089

-.222

.252

-.155

.960**

   

L 2–4 BMD

-.159

.019

-.330*

.036

.138

.226

.122

.072

-.118

.122

.084

  

Femur Neck BMD

-.112

-.043

-.246

.025

.105

.179

.067

.303*

-.034

.163

.097

.704**

 

Trochanter BMD

-.111

-.039

-.237

-.006

.123

.090

.017

.365**

-.125

.198

.125

.697**

.943**

 

TNF-α

IL-1β

IL-2r

IL-6

IL-8

PTH

s-CTX

ALP

Osteocalcin

ALT

AST

L 2–4 BMD

Femur Neck BMD

  1. ** Correlation is sigificant at the 0.01 level (2-tailed).
  2. * Correlation is significant at the 0.05 level (2-tailed).