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Table 2 Comparison of p16 protein expression to the p16 gene alterations.

From: Alterations of tumor suppressor gene p16 INK4ain pancreatic ductal carcinoma

Sr. No.

p16 protein expression

p16gene alteration

  

Deletion

Mutation

p16promoter methylation

1.

-

-

-

+ / -

2.

-

-

-

+ / -

3.

-

+

-

- / -

4.

-

-

+

- / +

5.

+

-

-

+ / +

6.

-

-

-

+ / -

7.

-

+

-

- / -

8.

-

-

-

+ / -

9.

-

-

-

+ / -

10.

+

-

+

- / +

11.

-

-

-

+ / -

12.

-

+

-

- / -

13.

-

-

-

+ / -

14.

+

-

-

+ / +

15.

-

-

-

+ / -

16.

-

-

-

- / +

17.

-

-

+

- / +

18.

-

-

-

+ / -

19.

+

-

-

- / +

20.

+

-

-

- / +

21.

-

-

 

+ / -

22.

+

-

+

- / +

23.

-

-

-

+ / -

24.

+

-

-

- / +

25.

-

-

-

- / +

  1. + / + : Completely methylated
  2. - / - : Unmethylated
  3. + / - : Partially methylated