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Table 2 Comparison of p16 protein expression to the p16 gene alterations.

From: Alterations of tumor suppressor gene p16 INK4ain pancreatic ductal carcinoma

Sr. No. p16 protein expression p16gene alteration
   Deletion Mutation p16promoter methylation
1. - - - + / -
2. - - - + / -
3. - + - - / -
4. - - + - / +
5. + - - + / +
6. - - - + / -
7. - + - - / -
8. - - - + / -
9. - - - + / -
10. + - + - / +
11. - - - + / -
12. - + - - / -
13. - - - + / -
14. + - - + / +
15. - - - + / -
16. - - - - / +
17. - - + - / +
18. - - - + / -
19. + - - - / +
20. + - - - / +
21. - -   + / -
22. + - + - / +
23. - - - + / -
24. + - - - / +
25. - - - - / +
  1. + / + : Completely methylated
  2. - / - : Unmethylated
  3. + / - : Partially methylated