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Figure 3 | BMC Gastroenterology

Figure 3

From: TGF β1 and PDGF AA override Collagen type I inhibition of proliferation in human liver connective tissue cells

Figure 3

Mitogenic effects of PDGF AA and TGF-β on SF and LCTC. A. Effect of increasing PDGF AA concentrations on growth of LCTC (black bars) and SF (gray bars) (n = 4). B. Effect of increasing concentrations of TGF-β on growth of LCTC (black bars) and SF (gray bars) (n = 4). (*) denotes significant difference between SF and LCTC; p0.05. C. Kinetics of DNA synthesis in LCTC as measured by [H3]-thymidine incorporation in the presence (filled circles) and absence (empty circles) of TGF-β (n = 4). Note second delayed peak of incorporation at 40 hr (black arrow). D. Kinetics of DNA synthesis in SF as measured by [H3]-thymidine incorporation in the presence (filled circles) and absence (empty circles) of TGF-β (n = 4). Note the absence of the second delayed peak of incorporation at 40 hr (black arrow).

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