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Figure 2 | BMC Gastroenterology

Figure 2

From: Transfection of IL-10 expression vectors into endothelial cultures attenuates α4β7-dependent lymphocyte adhesion mediated by MAdCAM-1

Figure 2

IL-10 gene transfected SVEC is resistant to TNF-α induced MAdCAM-1 expression. TNF-α (1 ng/ml, 24 h) significantly increased expression of MAdCAM-1 and this was significantly blocked by IL-10 gene transfection. Alone, IL-10 gene transfer had no effect on MAdCAM-1 expression (n = 5). (* p < 0.05 from TNF-α, # p < 0.05 from control). One-way ANOVA with Fisher's PLSD test.

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