A comparative study of gallstones from children and adults using FTIR spectroscopy and fluorescence microscopy

BMC Gastroenterology

Table 1 Type, occurrence and IR bands of principal component observed in gallstones

Type of Stone	Occurrence of stones^a (percents)	Principal component	Principal IR bands observed	Literature values (Reference 16).
Black I (adult)	18	Bilirubin	1661, 1626, 1570	1670,1640 (OC=O stretching) 1575(C=C stretching)
Black II (adult)		Cholesterol	3398,2933, 2866, 1463, 1376, 1053	3410,2925 (CH₂ and CH₃ asymmetric stretching) 2860 (CH₂ and CH₃ symmetric stretching) 1460,1380 (CH₂ and CH₃ bending) 1050(C-C stretching)
Black (child)	63	Bilirubin	1661,1626, 1571	Same as above
Brown (adult)	16	Cholesterol	3395,2936, 2899,2866, 1464,1372, 1052	Same as above
Green inner core (adult)	ND	Cholesterol	2933, 2899, 2866,1464, 1381,1052	Same as above
Mixed (adult)	ND	Cholesterol	3395,2933, 2866,1465, 1376,1056	Same as above

ND represents Not Determined. CaCo₃ present in green stone gives rise to two characteristic IR bands at 1445 and 875 cm^-1 due to C-O stretching and bending vibrations respectively, ^aThe listed numbers refer to adults or children.

ISSN: 1471-230X