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Table 2 Symptom improvement or resolution by study, time point and treatment group

From: Are proton pump inhibitors the first choice for acute treatment of gastric ulcers? A meta analysis of randomized clinical trials

   Improvement (%Resolved)
   Study Drug Comparator
Reference Symptom 2 wks 4 wks 2 wks 4 wks
Dekkers [26] Pain frequency 71 (34)1 82 (52)2 61 (29)1 65 (44)2
  Day pain 88 (60)1 90 (75)2 75 (59)1 83 (67) 2
  Night pain 82 (68)1 89 (84)2 79 (61)1 80 (68) 2
Witzel [25] Pain free 79 88 68 81
Florent [24] Daytime pain   863   603
  Night pain   100   70
Bardhan [15] Pain free   L30 = 75   65
    L60 = 72   
Michel [16] Epigastric pain relief   73   72
Valenzuela [13] Global assessment of GI symptoms   O40 = 49.3   
    O20 = 40.5   
Ital Coop Grp [19] Overall symptoms 75 87 65 80
  Epigastric day pain 94   92  
  Epigastric night pain 96   91  
Walan [20] Ulcer symptoms free O40 = 69   55  
   O20 = 62    
Cloud [14] Frequency of symptoms   Rab20=(64)2   (28)2
    Rab40=(46)2   
  Severity of daytime symptoms   Rab20=(62)2   (54)2
    Rab40=(57)2   
  Severity of nighttime symptoms   Rab20=(70)2   (65)2
    Rab40=(55)2   
  1. w = week, Rab = rabeprazole, L = lansoprazole, O = omeprazole. The number after the letter indicates the dose. 1: three weeks, 2: six weeks, 3: eight weeks.