Skip to main content

Table 1 Symptoms and endoscopic appearances in controls and inflammatory bowel disease

From: Paneth cell metaplasia in newly diagnosed inflammatory bowel disease in children

  Control UC CD
N 14 13 15
Sex (M/F) 10/4 6/7 5/10
Age range (median) 6-16 (12.5) 6-15 (14) 7-16 (13)
Symptoms: n (%) Diarrhoea 9 (64) 8 (62) 8 (53)
Abdominal pain 9 (64) 4 (31) 7 (47)
Rectal bleeding 6 (43) 10 (77) 6 (40)
Weight loss 4 (29) 6 (46) 2 (13)
Treatment prior to diagnosis: n (%) Antiinflammatories 2 (14) 7 (54)* 7 (47)
Infliximab 0 4 (31)* 0
Immunosuppressants 0 6 (46)† 1 (7)
Endoscopic appearance: n (%) Abnormal 1 (7)‡ 13 (100)§ 15 (100)§
Terminal ileitis 1 (7)‡ 0 5 (33)
Extensive colitis 0 7 (54)† 3 (20)
Discontinuous colitis 1 (7)‡ 1 (8) 7 (47)*
Left-sided colitis only 0 5 (38)* 0
  Recto-sigmoid colitis only 0 2 (15) 0
  1. *P < 0.05 (chi-squared) compared to controls.
  2. †P < 0.005 compared to controls.
  3. ‡Histology showed lymphonodular hyperplasia.
  4. §P < 0.00001 compared to controls.