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Table 5 Demographic and clinical characteristics of the responders and non-responders of IFX with CMV infection

From: Long-term efficacy of infliximab for refractory ulcerative colitis: results from a single center experience

Characteristics

Responders with CMV infection (n = 6)

Non-responders with CMV infection (n = 5)

p value

Sex (men/women), n (%)

4 (66.7)/2 (33.3)

2 (40.0)/3 (60.0)

0.38

Age (years)*

50.8 ± 16.2

41.4 ± 17.2

0.42

Disease duration (years)*

4.5 ± 4.8

10.2 ± 9.6

0.32

Modified Truelove and Witts severity index*

8.3 ± 1.7

12.4 ± 2.2

0.02

Mayo score (endoscopy)*

2.8 ± 0.4

3.0 ± 0.0

0.37

Extent of disease

   

  Left-side type, n (%)

2 (33.3)

0 (0.0)

0.15

  Extensive colitis, n (%)

4 (66.7)

5 (100.0)

Concomitant medications

   

  Corticoteroids, n (%)

0 (0.0)

1 (20.0)

0.25

  Azathioprine/Mercaptopurine, n (%)

3 (50.0)

2 (40.0)

0.74

  Tacrolimus, n (%)

1 (16.7)

4 (80.0)

0.04

  1. IFX: infliximab, CR: clinical remission, CRP: C-reactive protein.
  2. Result reported as number (%) of patients or *mean ± standard deviation.