Table 2 Incidence of KRAS mutations according to region
Mutation | Middle west n (%) | Northeast n (%) | North n (%) | Southeast n (%) | South n (%) |
|---|---|---|---|---|---|
195 (100) | 250 (100) | 49 (100) | 1,610 (100) | 515 (100) | |
Gly12Asp (GGT > GAT) | 79 (40.5) | 99 (39.6) | 15 (30.6) | 587 (36.5) | 174 (33.8) |
Gly12Val (GGT > GTT) | 48 (24.6) | 53 (21.2) | 16 (32.7) | 397 (24.7) | 124 (24.1) |
Gly12Cys (GGT > TGT) | 14 (7.2) | 21 (8.4) | 6 (12.2) | 114 (7.1) | 50 (9.7) |
Gly12Ala (GGT > GCT) | 12 (6.2) | 14 (5.6) | 1 (2) | 90 (5.6) | 32 (62) |
Gly12Ser (GGT > AGT) | 12 (6.2) | 24 (9.6) | 4 (8.2) | 125 (7.8) | 29 (5.6) |
Gly12Arg (GGT > CGT) | 6 (3.1) | 5 (2) | 2 (4.1) | 16 (1) | 5 (1) |
Gly13Asp (GGC > GAC) | 24 (2.3) | 34 (13.6) | 4 (8.2) | 264 (16.4) | 96 (18.6) |
Gly13Cys (GGC > TGC) | 0 | 0 | 0 | 11 (0.7) | 2 (0.4) |
Gly13Ser (GGC > AGC) | 0 | 0 | 1 (2) | 3 (0.2) | 1 (0.2) |
Gly13Val (GGC > GTT) | 0 | 0 | 0 | 1 (0.1) | 1 (0.2) |
Gly13Arg (GGC > CGC) | 0 | 0 | 0 | 2 (0.1) | 1 (0.2) |
Total/region (100) | 33.5% | 30.9% | 34.5% | 34.7% | 32.0% |