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Table 1 KEGG pathways of significantly differentially methylated genes

From: DNA methylation subgroups and the CpG island methylator phenotype in gastric cancer: a comprehensive profiling approach

Pathway Entry Pvalue (EASE score) Genes
Different between tumor and tumor-adjacent gastric tissue    
Pathways in cancer hsa05200 0.0000014 DCC, WNT5A, FGF5, RET, FGF8, FLT3, PPARG, TGFB3, FGF12, MMP2, GLI3, TGFB2, WNT2, SMO, CSF3R, HHIP, CCNA1, FGF2, FGF3
Hedgehog signaling pathway hsa04340 0.0015474 WNT2, WNT5A, SMO, HHIP, GLI3, BMP6
Cytokine-cytokine receptor interaction hsa04060 0.0019703 LIF, FLT1, FLT3, FLT4, IFNG, TGFB3, CSF3R, NGFR, KDR, TNFSF8, EPO, TGFB2
Basal cell carcinoma hsa05217 0.0096687 WNT2, WNT5A, SMO, HHIP, GLI3
Hematopoietic cell lineage hsa04640 0.0098799 CD34, FLT3, CD2, CSF3R, MME, EPO
MAPK signaling pathway hsa04010 0.0201135 FGF5, FGF8, RASGRF1, NTRK2, MOS, TGFB3, FGF12, FGF2, FGF3, TGFB2
Melanoma hsa05218 0.0229304 FGF5, FGF8, FGF12, FGF2, FGF3
TGF-beta signaling pathway hsa04350 0.0437881 IFNG, TGFB3, THBS2, BMP6, TGFB2
Regulation of actin cytoskeleton hsa04810 0.0456631 FGF5, FGF8, TIAM1, INS, MOS, FGF12, FGF2, FGF3
Axon guidance hsa04360 0.0471078 DCC, EPHA7, EPHA8, SEMA3C, FES, SLIT2
Different between tumor subtype H and L    
Pathways in cancer hsa05200 0.0000012 DCC, WNT5A, FGF5, FGF8, RET, FLT3, MMP2, GLI3, TGFB2, WNT2, SMO, HHIP, CCNA1, FGF3
Hedgehog signaling pathway hsa04340 0.0000843 WNT2, WNT5A, SMO, HHIP, GLI3, BMP6
Basal cell carcinoma hsa05217 0.0010110 WNT2, WNT5A, SMO, HHIP, GLI3
Cytokine-cytokine receptor interaction hsa04060 0.0194278 FLT1, FLT3, FLT4, NGFR, KDR, EPO, TGFB2