Table 1 Clinical and laboratory data of eight CD patients originating from the initial group of 450 FDR that disclosed seroconversion (Group II)
From: Screening for celiac disease in 1st degree relatives: a 10-year follow-up study
$Pts | Kinship | Age at 1sttest (y) | Age at 2ndtest (y) | Interval between 1stand 2ndtest (m) | tTG | EMA | HLA | #Marsh | Symptoms and associated disorders |
|---|---|---|---|---|---|---|---|---|---|
1 | Sister | 6 | 7 | 12 | 35.9 | Pos | DQA1*0501 | I | Irritability, constipation, recurrent abdominal pain |
DQB1*0201 | |||||||||
2 | Sister (twin) | 12 | 16 | 54 | 35.1 | Neg | DQA1*0501 | ND | Recurrent abdominal pain, frequent joint pain |
DQB1*0201 | |||||||||
DQA1*0301 | |||||||||
DQB1*0302 | |||||||||
3 | Sister | 30 | 37 | 88 | 123.6 | Pos | DQA1*0501 | III | Bouts of diarrhea, recurrent abdominal pain, bloating, anemia |
DQB1*0201 | |||||||||
4 | Mother | 30 | 37 | 84 | 46.5 | Neg | DQA1*0501 | ND | Bouts of diarrhea, aphthous ulcers, bloating, joint pain |
DQB1*0201 | |||||||||
5 | Sister | 32 | 35 | 38 | 57,1 | Neg | DQA1*0501 | ND | Asymptomatic |
DQB1*0201 | |||||||||
6 | Sister | 37 | 39 | 26 | 81.7 | Pos | DQA1*0501 | I | Bloating, constipation, aphtous ulcers, fatigue |
DQB1*0201 | |||||||||
7 | Sister and daughter | 37 | 44 | 89 | 95.6 | Pos | DQB1*0201 | III | Asymptomatic |
DQA1*0301 | |||||||||
DQB1*0302 | |||||||||
8 | Father | 67 | 75 | 89 | 65.9 | Pos | DQA1*0501 | II | Asymptomatic |
DQB1*0201 |