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Table 1 Baseline clinical, demographic, histologic and metabolic characteristics of 77 patients with chronic hepatitis C

From: Serum levels of apoptosis inhibitor of macrophage are associated with hepatic fibrosis in patients with chronic hepatitis C

Patients (number)

77

Age (years)

56.1 ± 12.4

Sex [male/female]

31/46

Body mass index (kg/m2)

23.5 ± 2.9

 Male (kg/m2)

23.8 ± 2.9

 Female (kg/m2)

23.3 ± 3.1

HCV serotype [I/II]

47/30

Viral load of HCV (log IU/ml)

5.9 ± 1.1

Platelet count (×104/μl)

18.1 ± 7.2

Total cholesterol (mg/dl)

170.7 ± 38.6

Albumin (g/dl)

4.3 ± 0.4

ALT (IU/l)

64.5 ± 53.9

γ-GTP (IU/l)

50.1 ± 62.2

Diabetes [absent/present]

60/17

Hemoglobin A1c (%)

5.4 ± 0.6 (n = 75)

Fasting plasma glucose (mg/dl)

97.0 ± 22.1

Fasting insulin (μU/ml)

9.8 ± 5.7 (n = 40)

HOMA-IR

2.2 ± 1.5 (n = 40)

Leptin (ng/ml)

7.6 ± 5.1

Adiponectin (ng/ml)

9.0 ± 6.2

Resistin (ng/ml)

8.5 ± 4.6

AIM (μg/ml)

1.39 ± 0.86

Hyaluronic acid (ng/ml)

95.9 ± 114.0 (n = 75)

α-fetoprotein (ng/ml)

7.1 ± 11.2

Histologic characteristics

 

 Activity [A0-1/2-3]

32/45

 Fibrosis [F0-1/2-3]

36/41

 Steatosis [<5%/≥5%]

59/18

  1. Data are shown as the means ± standard deviations or number.
  2. HCV, hepatitis C virus; ALT, alanine aminotransferase; γ-GTP, γ-glutamyl transpeptidase; HOMA-IR, homeostasis model assessment-insulin resistance; AIM, apoptosis inhibitor of macrophage.