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Table 1 Baseline characteristics of CVS patients based on time of onset of symptoms

From: Quantitative pedigree analysis and mitochondrial DNA sequence variants in adults with cyclic vomiting syndrome

Variables

Available N

Pediatric N-35

Adolescent N-30

Adults N-151

P-value

Age (Years)

216

26

22

39

<0.001**

Gender

216

   

0.006¥*

Male

 

14% (5)

20% (6)

38% (58)

 

Female

 

86% (30)

80% (24)

62% (93)

 

Race

196

   

0.293¥

White

 

100%

89% (25)

96% (129)

 

Black

 

(33)

0% (0)

0% (0)

 

Hispanic

 

0% (0)

7% (2)

3% (4)

 

Other

 

0% (0)

4% (1)

1% (2)

 

Hispanic Other

     

Geographical Location

189

   

0.024¥*

Canada

 

4% (1)

0% (0)

0% (0)

 

Midwest

 

56% (15)

76% (22)

74% (98)

 

Northeast

 

22% (6)

3% (1)

4% (5)

 

South

 

7% (2)

7% (2)

13% (17)

 

United Kingdom

 

4% (1)

0% (0)

1% (1)

 

West

 

7% (2)

14% (4)

9% (12)

 

Type of CVS

181

   

0.001¥*

CVS Plus

 

12% (3)

7% (2)

0% (0)

 

Classical CVS

 

76% (19)

76% (22)

93% (118)

 

Catamenial CVS

 

12% (3)

17% (5)

7% (9)

 

Personal history of migraine

213

   

0.819¥

No

 

58% (19)

57% (17)

62% (93)

 

Yes

 

42% (14)

43% (13)

38% (57)

 

Family history of migraine

180

   

0.019¥*

No

 

48% (12)

36% (10)

63% (80)

 

Yes

 

52% (13)

64% (18)

37% (47)

 

Emergency room/urgent care visits/year

192

2

4.5

4

0.411

Hospital Admissions/year

140

1

1

2

0.729

Surgery related to CVS

182

   

0.715¥

No

 

78% (21)

68% (19)

72% (91)

 

Yes

 

22% (6)

32% (9)

28% (36)

 

Disability

180

   

0.421¥

No

 

89% (24)

89% (25)

80%

 

Yes

 

11% (3)

11% (3)

(100) 20% (25)

 

Prophylactic medications

177

   

0.255¥

No

 

4% (1)

12% (3)

4% (5)

 

Yes

 

96% (26)

88% (23)

96% (119)

 

Response to therapy

105

   

0.613^

None

 

7% (1)

24% (4)

20% (15)

 

Partial

 

29% (4)

24% (4)

26% (19)

 

Complete

 

64% (9)

52% (9)

54% (40)

 
  1. Median values represented for continuous variables. Numbers after percent’s are frequencies. Tests used: Kruskal-Wallis test; ¥Fisher’s exact test; ^Proportional odds likelihood ratio test.
  2. *Indicates a P value <0.05.
  3. **Indicates a P value < 0.001.