Skip to main content

Table 1 Baseline characteristics of CVS patients based on time of onset of symptoms

From: Quantitative pedigree analysis and mitochondrial DNA sequence variants in adults with cyclic vomiting syndrome

Variables Available N Pediatric N-35 Adolescent N-30 Adults N-151 P-value
Age (Years) 216 26 22 39 <0.001**
Gender 216     0.006¥*
Male   14% (5) 20% (6) 38% (58)  
Female   86% (30) 80% (24) 62% (93)  
Race 196     0.293¥
White   100% 89% (25) 96% (129)  
Black   (33) 0% (0) 0% (0)  
Hispanic   0% (0) 7% (2) 3% (4)  
Other   0% (0) 4% (1) 1% (2)  
Hispanic Other      
Geographical Location 189     0.024¥*
Canada   4% (1) 0% (0) 0% (0)  
Midwest   56% (15) 76% (22) 74% (98)  
Northeast   22% (6) 3% (1) 4% (5)  
South   7% (2) 7% (2) 13% (17)  
United Kingdom   4% (1) 0% (0) 1% (1)  
West   7% (2) 14% (4) 9% (12)  
Type of CVS 181     0.001¥*
CVS Plus   12% (3) 7% (2) 0% (0)  
Classical CVS   76% (19) 76% (22) 93% (118)  
Catamenial CVS   12% (3) 17% (5) 7% (9)  
Personal history of migraine 213     0.819¥
No   58% (19) 57% (17) 62% (93)  
Yes   42% (14) 43% (13) 38% (57)  
Family history of migraine 180     0.019¥*
No   48% (12) 36% (10) 63% (80)  
Yes   52% (13) 64% (18) 37% (47)  
Emergency room/urgent care visits/year 192 2 4.5 4 0.411
Hospital Admissions/year 140 1 1 2 0.729
Surgery related to CVS 182     0.715¥
No   78% (21) 68% (19) 72% (91)  
Yes   22% (6) 32% (9) 28% (36)  
Disability 180     0.421¥
No   89% (24) 89% (25) 80%  
Yes   11% (3) 11% (3) (100) 20% (25)  
Prophylactic medications 177     0.255¥
No   4% (1) 12% (3) 4% (5)  
Yes   96% (26) 88% (23) 96% (119)  
Response to therapy 105     0.613^
None   7% (1) 24% (4) 20% (15)  
Partial   29% (4) 24% (4) 26% (19)  
Complete   64% (9) 52% (9) 54% (40)  
  1. Median values represented for continuous variables. Numbers after percent’s are frequencies. Tests used: Kruskal-Wallis test; ¥Fisher’s exact test; ^Proportional odds likelihood ratio test.
  2. *Indicates a P value <0.05.
  3. **Indicates a P value < 0.001.