Table 5 Correlation between objective (pH) and patient reported subjective outcomes in study patients PPI group on PPIs (6 months following high-dose PPI therapy)
Parameters | Regurgitation | RSI | GERD-HRQL | DMS | % total time | RE |
|---|---|---|---|---|---|---|
Regurgitation | 1.00 | |||||
RSI | 0.70 (<0.001) | 1.00 | ||||
GERD-HRQL | 0.59 (0.005) | 0.71 (<0.001) | 1.00 | |||
DMS | −0.20 (0.399) | 0.05 (0.838) | 0.38 (0.107) | 1.00 | ||
% total time | −0.12 (0.619) | 0.12 (0.598) | 0.41 (0.063) | 0.94 (<0.001) | 1.00 | |
RE | 0.10 (0.667) | 0.31 (0.167) | 0.46 (0.035) | 0.77 (<0.001) | 0.84 (<0.001) | 1.00 |
Crossover patients off PPIs (6 months following transoral fundoplication) | ||||||
Parameters | Regurgitation | RSI | GERD-HRQL | DMS | % total time | RE |
Regurgitation | 1.00 | |||||
RSI | 0.71 (<0.001) | 1.00 | ||||
GERD-HRQL | 0.81 (<0.001) | 0.62 (0.003) | 1.00 | |||
DMS | 0.18 (0.428) | 0.14 (0.556) | 0.04 (0.866) | 1.00 | ||
% total time | 0.11 (0.637) | 0.09 (0.705) | 0.08 (0.746) | 0.89 (<0.001) | 1.00 | |
RE | 0.17 (0.461) | 0.14 (0.546) | 0.14 (0.543) | 0.65 (0.001) | 0.80 (<0.001) | 1.00 |
TF group off PPIs (12 months following transoral fundoplication) | ||||||
Parameters | Regurgitation | RSI | GERD-HRQL | DMS | % total time | RE |
Regurgitation | 1.00 | |||||
RSI | 0.66 (<0.001) | 1.00 | ||||
GERD-HRQL | 0.42 (0.010) | 0.73 (<0.001) | 1.00 | |||
DMS | 0.02 (0.885) | 0.10 (0.550) | 0.35 (0.036) | 1.00 | ||
% total time | 0.06 (0.724) | 0.10 (0.552) | 0.39 (0.018) | 0.98 (<0.001) | 1.00 | |
RE | 0.21 (0.216) | 0.13 (0.424) | 0.41 (0.013) | 0.83 (<0.001) | 0.84 (<0.001) | 1.00 |