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Table 3 Distribution of primary and secondary study endpoints as well as preservation solutions to the different eras, 580 patients from the Kiel liver transplant program

From: Comparable outcome of liver transplantation with Histidine-Tryptophan-Ketoglutarate vs. University of Wisconsin preservation solution: a retrospective observational double-center trial

 

Era

I

II

III

IV

p-value

n (%)

9 (1.6%)

96 (16.6%)

152 (26.2%)

323 (55.7%)

n.a.

HTK

0 (0%)

8 (8.3%)

68 (44.7%)

281 (87.0%)

<0.0011

UW

9 (100.0%)

88 (91.7%)

84 (55.3%)

42 (13%)

<0.0011

3 months mortality

3 (33.3%)

22 (22.9%)

35 (23.0%)

32 (9.9%)

<0.0011

graft loss

8 (88.9%)

59 (61.5%)

75 (49.7%)

85 (26.5%)

<0.0011

3 month graft survival

6 (66.7%)

68 (70.8%)

106 (69.7%)

262 (81.1%)

0.0211

Biliary complications

1 (11.1%)

33 (34.4%)

47 (30.9%)

18 (19.4%)

0.0991

  1. HTK = Histidine-Tryptophane-Ketoglutarate solution; UW = University of Wisconsin solution; SD = Standard Deviation.
  2. 1Pearson’s Chi2 Test.