Table 3 Correlations of AFP, ALT, AST, GGT, and APRI with inflammation and fibrosis stages
AFP (ng/ml) | ALT (U/L) | AST (U/L) | GGT (UL) | APRI (AST/PLT ratio) | ||
|---|---|---|---|---|---|---|
Inflammation stage | 0-1 | 2.7 (1.6, 5.2) | 49.0 (29.0, 94.0) | 31.0 (24.0, 58.0) | 33.0 (20.0, 62.0) | 0.17 (0.11, 0.40) |
2 | 3.1 (2.1, 4.7) | 85.5 (41.0, 155.0) | 48.5 (32.0, 85.0) | 38.5 (27.0, 63.0) | 0.26 (0.15, 0.49) | |
3 | 5.5 (2.9, 13.5) | 114.0 (51.0, 284.0) | 79.0 (42.0, 148.0) | 57.0 (35.0, 96.0) | 0.52 (0.27, 0.89) | |
4 | 24.3 (4.9, 108.2) | 132.5 (61.0, 306.0) | 97.0 (56.0, 172.0) | 90.0 (58.0, 144.0) | 0.73 (0.42, 1.50) | |
Spearman's ρ | 0.436* | 0.271* | 0.393* | 0.361* | 0.445* | |
Fibrosis stage | 0-1 | 3.0 (1.9, 5.2) | 78.0 (35.0, 171.0) | 44.0 (29.0, 88.0) | 38.0 (23.0, 64.0) | 0.25 (0.13, 0.49) |
2 | 3.4 (2.3, 6.1) | 113.5 (57.5, 281.0) | 74.5 (43.5, 136.0) | 52.0 (30.0, 83.0) | 0.40 (0.21, 0.76) | |
3 | 5.4 (2.9, 16.6) | 120.0 (51.0, 324.0) | 75.0 (41.0, 169.0) | 61.0 (32.0, 106.0) | 0.53 (0.22, 1.14) | |
4 | 11.3 (3.8, 59.5) | 84.0 (44.0, 187.0) | 67.0 (41.0, 131.0) | 66.0 (40.0, 118.0) | 0.54 (0.29, 1.02) | |
Spearman's ρ | 0.404* | 0.021 | 0.137* | 0.237* | 0.281* |