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Table 2 Oral zinc supplementation reduced diarrheal scores following lactulose-induced osmotic diarrhea

From: Zinc treatment ameliorates diarrhea and intestinal inflammation in undernourished rats

Day UN N = 11 UN + Zn N = 12 P UN + Lac N = 12 UN + Lac + Zn N = 12 P
8 0 (0–0) 0 (0–0) ns 0 (0–0) 0 (0–0) ns
9 0 (0–0) 0 (0–0) ns 2 (0–4) 1 (0–4) ns
10 0 (0–0) 0 (0–0) ns 1 (0–3) 0 (0–1)* <0.05
11 0 (0–0) 0 (0–0) ns 2 (1–4) 0.5 (0–4)* <0.05
12 0 (0–0) 0 (0–0) ns 2 (1–4) 0.5 (0–4)* <0.05
13 0 (0–0) 0 (0–0) ns 2 (0–4) 0 (0–4)* <0.05
14 0 (0–0) 0 (0–0) ns 2 (1–4) 1 (0–2)* <0.05
  1. Normal stools: normal texture, consistency, and dryness.
  2. Diarrhea scores: + = wet stools; ++ = pasty stools; +++ = semiliquid stools; ++++ = watery diarrhea.
  3. Data are reported as median score. The score total range is shown in parenthesis. Data were analyzed by Kruskal-Wallis and Dunns post-test.
  4. Groups: UN = undernourished controls; UN + Zn = undernourished rats treated with oral zinc acetate (500 mg/L); UN + Lac = undernourished rats challenged by saturated lactose (30 g/Kg); UN + Lac + Zn = Zinc-treated undernourished rats challenged by saturated lactose (30 g/Kg).