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Table 6 Intention-to-treat analysis for quality of life

From: Treatment with pirfenidone for two years decreases fibrosis, cytokine levels and enhances CB2 gene expression in patients with chronic hepatitis C

Domains (mean ± SD)

SF-36* before

SF-36* after

P value

Physical function

69 ± 30

82 ± 23

0.00**

Role physical

61 ± 47

86 ± 32

0.02**

Body pain

70 ± 26

81 ± 19

0.00**

General health

55 ± 21

73 ± 18

0.00**

Vitality

62 ± 24

73 ± 22

0.02**

Social functioning

73 ± 29

81 ± 23

0.03**

Role emotional

68 ± 45

83 ± 38

0.17

Mental health

75 ± 20

83 ± 17

0.00**

  1. *SF-36: Short-Form Health Survey with 36 questions. **p < 0,05.