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Table 3 Occurrence of atypical GERD Symptoms in the 5 classes (primary efficacy set N = 7434)

From: Classification of adults suffering from typical gastroesophageal reflux disease symptoms: contribution of latent class analysis in a European observational study

 

Class 1

Class 2

Class 3

Class 4

Class 5

n (%)

N = 1598

N = 845

N = 2375

N = 1181

N = 1435

Digestive GERD symptoms

     

 Reported any atypical digestive symptom*

1536 (96.1)

656 (77.6)

1972 (83.0)

1097 (92.9)

652 (45.4)

 Slow digestion/early satiety

880 (55.1)

285 (33.7)

874 (36.8)

516 (43.7)

203 (14.1)

 Other digestive symptoms

197 (12.3)

75 (8.9)

208 (8.8)

114 (9.7)

169 (11.8)

 Epigastralgia

1004 (62.8)

326 (38.6)

1045 (44.0)

474 (40.1)

305 (21.3)

 Eructation

1037 (64.9)

331 (39.2)

1042 (43.9)

566 (47.9)

147 (10.2)

 Nausea

508 (31.8)

125 (14.8)

410 (17.3)

217 (18.4)

125 (8.7)

Non-Digestive GERD symptoms

    

 Thoracic manifestations1

643 (40.3)

127 (15.0)

168 (7.1)

116 (9.8)

71 (5.0)

 Pulmonary symptoms2

971 (60.8)

216 (25.6)

138 (5.8)

74 (6.3)

123 (8.6)

 ENT symptoms3

1181 (73.9)

227 (26.9)

40 (1.7)

168 (14.2)

167 (11.7)

  1. N = number of subjects.
  2. n = number of subjects with observations.
  3. ENT = ears, nose, throat.
  4. *Subjects could report more than one atypical digestive symptom.
  5. 1Atypical precordial pain.
  6. 2Cough, etc.
  7. 3Hoarseness, pharyngeal pain, globus, etc.