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Table 3 Occurrence of atypical GERD Symptoms in the 5 classes (primary efficacy set N = 7434)

From: Classification of adults suffering from typical gastroesophageal reflux disease symptoms: contribution of latent class analysis in a European observational study

  Class 1 Class 2 Class 3 Class 4 Class 5
n (%) N = 1598 N = 845 N = 2375 N = 1181 N = 1435
Digestive GERD symptoms      
 Reported any atypical digestive symptom* 1536 (96.1) 656 (77.6) 1972 (83.0) 1097 (92.9) 652 (45.4)
 Slow digestion/early satiety 880 (55.1) 285 (33.7) 874 (36.8) 516 (43.7) 203 (14.1)
 Other digestive symptoms 197 (12.3) 75 (8.9) 208 (8.8) 114 (9.7) 169 (11.8)
 Epigastralgia 1004 (62.8) 326 (38.6) 1045 (44.0) 474 (40.1) 305 (21.3)
 Eructation 1037 (64.9) 331 (39.2) 1042 (43.9) 566 (47.9) 147 (10.2)
 Nausea 508 (31.8) 125 (14.8) 410 (17.3) 217 (18.4) 125 (8.7)
Non-Digestive GERD symptoms     
 Thoracic manifestations1 643 (40.3) 127 (15.0) 168 (7.1) 116 (9.8) 71 (5.0)
 Pulmonary symptoms2 971 (60.8) 216 (25.6) 138 (5.8) 74 (6.3) 123 (8.6)
 ENT symptoms3 1181 (73.9) 227 (26.9) 40 (1.7) 168 (14.2) 167 (11.7)
  1. N = number of subjects.
  2. n = number of subjects with observations.
  3. ENT = ears, nose, throat.
  4. *Subjects could report more than one atypical digestive symptom.
  5. 1Atypical precordial pain.
  6. 2Cough, etc.
  7. 3Hoarseness, pharyngeal pain, globus, etc.