Table 1 Number of subjects for each indicator variable (primary efficacy set N = 7434)
n (%) | |
|---|---|
S1: daytime heartburn | 6319 (85.0) |
S2: daytime regurgitation | 5217 (70.2) |
S3: nighttime heartburn and/or nighttime regurgitation | 4540 (61.1) |
S4: nausea, eructation | 3852 (51.8) |
S5: slow digestion, early satiety | 2758 (37.1) |
S6: epigastralgia | 3154 (42.4) |
S7: dysphagia, vomiting | 1169 (15.7) |
S8: digestive bleeding, anemia* | 124 (1.7) |
S9: thoracic manifestations (atypical precordial pain) | 1125 (15.1) |
S10: respiratory disturbances (cough) | 1522 (20.5) |
S11: ENT symptoms (hoarseness, pharyngeal pain, globus, etc.) | 1783 (24.0) |
S12: early awakening, difficulty falling asleep | 2003 (26.9) |
S13: nocturnal awakening, nightmares | 2799 (37.7) |