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Table 1 Number of subjects for each indicator variable (primary efficacy set N = 7434)

From: Classification of adults suffering from typical gastroesophageal reflux disease symptoms: contribution of latent class analysis in a European observational study

  n (%)
S1: daytime heartburn 6319 (85.0)
S2: daytime regurgitation 5217 (70.2)
S3: nighttime heartburn and/or nighttime regurgitation 4540 (61.1)
S4: nausea, eructation 3852 (51.8)
S5: slow digestion, early satiety 2758 (37.1)
S6: epigastralgia 3154 (42.4)
S7: dysphagia, vomiting 1169 (15.7)
S8: digestive bleeding, anemia* 124 (1.7)
S9: thoracic manifestations (atypical precordial pain) 1125 (15.1)
S10: respiratory disturbances (cough) 1522 (20.5)
S11: ENT symptoms (hoarseness, pharyngeal pain, globus, etc.) 1783 (24.0)
S12: early awakening, difficulty falling asleep 2003 (26.9)
S13: nocturnal awakening, nightmares 2799 (37.7)
  1. n = number of subjects with observations.
  2. ENT = ears, nose, throat.
  3. *Indicator variable S8 (digestive bleeding, anemia) was not included in the latent class analysis.