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Table 2 Clinical, histological, and endoscopic findings in patients diagnosed with both eosinophilic esophagitis (EoE) and celiac disease (CD)

From: The association between celiac disease and eosinophilic esophagitis in children and adults

 

Patient # 1

Patient # 2

Patient # 3

Symptoms

Food bolus obstruction and heartburn

Abdominal pain and reflux

Intermittent vomiting

Age at diagnosis

14 EoE / 14 CD

15 EoE / 15 CD

11 EoE / 11 CD

pH study

Normal

Normal

PPI

Yes

Yes

Other diagnoses

Asthma, allergies

Atopy, food allergies

Endoscopy findings

   

Esophagus

Nodular mucosa and linear furrowing

Linear furrowing and adherent white plaques

Linear furrowing

Duodenum

“Scalloping” of the duodenum

Normal

Normal

Histology findings

   

Esophagus

>15 EoE per HPF

>15 EoE per HPF

>15 EoE per HPF

Duodenum

Marsh III

Marsh IIIb

Marsh III

Gluten restriction

Normalized

Improved

Normalized

  1. PPI, proton pump inhibitor.