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Table 2 Clinical, histological, and endoscopic findings in patients diagnosed with both eosinophilic esophagitis (EoE) and celiac disease (CD)

From: The association between celiac disease and eosinophilic esophagitis in children and adults

  Patient # 1 Patient # 2 Patient # 3
Symptoms Food bolus obstruction and heartburn Abdominal pain and reflux Intermittent vomiting
Age at diagnosis 14 EoE / 14 CD 15 EoE / 15 CD 11 EoE / 11 CD
pH study Normal Normal
PPI Yes Yes
Other diagnoses Asthma, allergies Atopy, food allergies
Endoscopy findings    
Esophagus Nodular mucosa and linear furrowing Linear furrowing and adherent white plaques Linear furrowing
Duodenum “Scalloping” of the duodenum Normal Normal
Histology findings    
Esophagus >15 EoE per HPF >15 EoE per HPF >15 EoE per HPF
Duodenum Marsh III Marsh IIIb Marsh III
Gluten restriction Normalized Improved Normalized
  1. PPI, proton pump inhibitor.