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Table 1 Summary of macroscopic evaluation data and bioelectrical measurements (R te ) of rectal biopsies vs. bowel preparation and biopsy forceps

From: Rectal forceps biopsy procedure in cystic fibrosis: technical aspects and patients perspective for clinical trials feasibility

Bowel Preparation

NaCl 0.9%

Glycerol 12%

Mannitol 20%

Biopsy Forceps

Jumbo

Standard

Jumbo

Standard

Jumbo

Standard

Tissue integrity

1.00 ± 0.11

2.00 ± 0.35

1.48 ± 0.31

2.21 ± 0.23

1.02 ± 0.02

1.97 ± 0.30

Friability

1.23 ± 0.12

1.36 ± 0.24

1.50 ± 0.31

1.81 ± 0.22

1.13 ± 0.33

1.33 ± 0.25

Bleeding

1.01 ± 0.08

1.21 ± 0.18

1.27 ± 0.21

1.16 ± 0.29

1.05 ± 0.22

0.83 ± 0.32

Mucus

1.12 ± 0.11

1.18 ± 0.17

0.91 ± 0.24

0.88 ± 0.13

0.74 ± 0.13

1.06 ± 0.13

Sub-mucosa (n)

Yes

16

3

3

1

2

1

No

42

9

4

4

12

10

R te (Ω.cm 2 )

21.82 ± 1.03

14.37 ± 1.21

18.75 ± 2.66

13.57 ± 2.70

18.69 ± 0.98

13.32 ± 1.11

  1. NOTE: Results are mean ± SEM; n = 107.