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Table 4 The frequency of the polymorphism D19H in the gallstone carriers and controls of the population from Stuttgart

From: Role of the ABCG8 19H risk allele in cholesterol absorption and gallstone disease

Group Controls (134) Gallstone carriers (34) (GG<>Gc)
Genotype G/G G/c c/c G/G G/c c/c P-value OR (95% CI)
Total 115 19 0 23 11 0 0.022 2.9(CI: 1.216 to 6.889)
Normal weight 66 9 0 9 2 0 0.627 1.6(CI: 0.303 to 8.770)
Overweight 49 10 0 14 9 0 0.043 3.2(CI: 1.071 to 9.264)
  1. G = major allele, c = minor allele, OR = odds ratio, CI = confidence interval.
  2. Statistical analysis of genotype frequency differences between gallstone carriers and controls was done using Fisher’s exact test. Odds ratios (ORs) together with a 95% confidence interval (CI) are given as risk measures for the development of gallstones. All statistical tests were two-tailed and a P-value of <0.05 was considered as statistically significant.