Skip to main content

Table 3 Characteristics of esophageal lesions and diagnostic performance of endoscopy

From: Risk factors for second primary neoplasia of esophagus in newly diagnosed head and neck cancer patients: a case–control study

Esophageal lesions

No. (%)

Histopathology

 

 Total biopsied lesions

60 (100.0)

 Chronic inflammation

3 (5.0)

 Squamous hyperplasia

17 (28.3)

 LGIN

11 (18.3)

 HGIN

14 (23.3)

 Invasive carcinoma

12 (20.0)

 Others

3 (5.0)

Detection of neoplasia *

No. (%)

Sensitivity/ Specificity/Accuracy (%)

Endoscopy/ Histopathology

60/37 (100)

-

 WLI

24/19 (51.4)

51.4 / 78.3 / 61.7

 NBI-ME

37/36 (97.3)

97.3 / 94.1 / 96.3

 LC

48/36 (97.3)

97.3 / 52.2 / 81.7

Location

 

 Upper third

9 (15.0)

 Middle third

26 (43.3)

 Lower third

25 (41.7)

No. of patients with synchronous lesions

 

 Single

46 (86.8)

 Multifocal

7 (13.2)

  1. Abbreviation: WLI white-light imaging, NBI-ME narrow-band imaging system with magnifying endoscopy, LC Lugol’s chromoendoscopy, LGIN low-grade intraepithelial neoplasia, HGIN high-grade intraepithelial neoplasia.
  2. *Detection of low-grade, high-grade intraepithelial neoplasia and invasive carcinoma by histological confirmation.