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Table 3 PTPN11 polymorphisms for H. pylori seropositivity in control

From: Association of polymorphism of PTPN 11 encoding SHP-2 with gastric atrophy but not gastric cancer in Helicobacter pylori seropositive Chinese population

Genotype Hp + (%) Hp-(%) OR(95%CI)* Pvalue
  (n = 459) (n = 464)   
rs2301756     
GG 74.7 75.2 Reference  
GA 23.3 22.8 1.18(0.51-2.72) 0.71
AA 2.0 2.0 1.52(0.49-4.66) 0.47
rs12423190     
T/T 52.1 50.7 Reference  
T/C 39.2 40.1 0.98(0.55-1.76) 0.95
C/C 8.7 9.2 0.92(0.29-2.93) 0.89
rs12229892     
G/G 32.9 34.6 Reference  
G/A 50.6 46.8 1.25(0.93-1.70) 0.15
A/A 16.5 18.5 1.01(0.65-1.57) 0.97
rs7958372     
T/T 74.7 74.9 Reference  
T/C 23.8 23.2 0.84(0.40-1.77) 0.65
C/C 1.5 1.8 0.61(0.13-2.79) 0.53
rs4767860     
A/A 33.8 33.0 Reference  
A/G 48.1 48.3 1.11(0.36-3.45) 0.86
G/G 18.1 18.7 1.00(0.55-1.84) 0.99
Haplotpe     
GTATA 41.0 41.6 Reference  
GCGTG 26.9 28.4 0.97(0.79-1.20) 0.77
GTGTA 15.7 14.8 1.08(0.83-1.40) 0.56
ATGCG 12.3 13.0 0.94(0.71-1.24) 0.66
Others 4.1 2.2   
  1. *OR for each genotype and hapolotype were calculated by age and sex adjusted logistic regression model.