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Table 3 PTPN11 polymorphisms for H. pylori seropositivity in control

From: Association of polymorphism of PTPN 11 encoding SHP-2 with gastric atrophy but not gastric cancer in Helicobacter pylori seropositive Chinese population

Genotype

Hp + (%)

Hp-(%)

OR(95%CI)*

Pvalue

 

(n = 459)

(n = 464)

  

rs2301756

    

GG

74.7

75.2

Reference

 

GA

23.3

22.8

1.18(0.51-2.72)

0.71

AA

2.0

2.0

1.52(0.49-4.66)

0.47

rs12423190

    

T/T

52.1

50.7

Reference

 

T/C

39.2

40.1

0.98(0.55-1.76)

0.95

C/C

8.7

9.2

0.92(0.29-2.93)

0.89

rs12229892

    

G/G

32.9

34.6

Reference

 

G/A

50.6

46.8

1.25(0.93-1.70)

0.15

A/A

16.5

18.5

1.01(0.65-1.57)

0.97

rs7958372

    

T/T

74.7

74.9

Reference

 

T/C

23.8

23.2

0.84(0.40-1.77)

0.65

C/C

1.5

1.8

0.61(0.13-2.79)

0.53

rs4767860

    

A/A

33.8

33.0

Reference

 

A/G

48.1

48.3

1.11(0.36-3.45)

0.86

G/G

18.1

18.7

1.00(0.55-1.84)

0.99

Haplotpe

    

GTATA

41.0

41.6

Reference

 

GCGTG

26.9

28.4

0.97(0.79-1.20)

0.77

GTGTA

15.7

14.8

1.08(0.83-1.40)

0.56

ATGCG

12.3

13.0

0.94(0.71-1.24)

0.66

Others

4.1

2.2

  
  1. *OR for each genotype and hapolotype were calculated by age and sex adjusted logistic regression model.
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BMC Gastroenterology

ISSN: 1471-230X

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