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Table 2 PTPN11 polymorphisms among H. pylori (+) subjects

From: Association of polymorphism of PTPN 11 encoding SHP-2 with gastric atrophy but not gastric cancer in Helicobacter pylori seropositive Chinese population

Genotype Control (%) Gastric atrophy (%) OR(95%CI)* Pvalue Gastric cancer (%) OR(95%CI)* Pvalue
  n = 459 n = 82    n = 291   
rs2301756        
GG 74.3 76.8 Reference   73.9 Reference  
GA 23.5 22.0 0.90(0.51-1.59) 0.72 37.9 0.92(0.62-1.35) 0.66
A/A 2.2 1.2 0.51(0.06-4.09) 0.53 3.4 1.26(0.47-3.37) 0.65
rs12423190        
TT 52.5 50.0 Reference   50.9 Reference  
TC 40.1 34.1 0.93(0.55-1.57) 0.78 41.2 1.18(0.64-2.18) 0.60
CC 7.4 15.9 2.20(1.06-4.55) 0.03 7.9 1.30(0.93-1.83) 0.13
TT/TC 92.6 84.1 Reference   92.1 Reference  
CC 7.4 15.9 2.47(1.13-4.55) 0.02 7.9 1.21(0.89-1.76) 0.15
rs12229892        
GG 32.2 36.6 Reference   30.6 Reference  
GA 51.2 47.6 0.82(0.49-1.39) 0.46 52.2 1.04(0.72-1.51) 0.82
AA 16.6 15.9 0.86(0.42-1.75) 0.67 17.2 1.02(0.63-1.67) 0.93
rs7958372        
TT 74.1 78.0 Reference   74.2 Reference  
TC 24.4 20.7 0.80(0.45-1.43) 0.46 24.1 0.94(0.64-1.37) 0.74
CC 1.5 1.2 0.83(0.10-7.01) 0.86 1.7 1.16(0.30-4047) 0.83
rs4767860        
AA 33.8 34.1 Reference   31.9 Reference  
AG 49.5 40.2 1.54(0.82-2.91) 0.18 51.9 1.04(0.70-1.88) 0.59
GG 16.8 25.6 0.80(0.46-1.38) 0.43 16.2 1.32(0.92-1.90) 0.14
Haplotpe        
GTATA 41.3 39.6 Reference   41.2 Reference  
GCGTG 26.0 32.3 1.36(0.92-2.02) 0.12 27.6 1.12(0.80-1.57) 0.51
GTGTA 16.0 14.0 0.96(0.58-1.61) 0.89 14.4 1.14(0.88-1.47) 0.32
ATGCG 12.4 11.6 1.03(0.59-1.78) 0.92 13.1 0.96(0.71-1.32) 0.82
Others 4.3 2.5    3.7   
  1. *OR for each genotype and hapolotype were calculated by age and sex adjusted logistic regression model.