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Table 4 Association between the genotype of the NFKB1 rs4648068 polymorphism and patient characteristics

From: Association of an NFKB1 intron SNP (rs4648068) with gastric cancer patients in the Han Chinese population

  N GG AOR (95%CI)Δ PvalueΔ GA AOR (95%CI)Δ PvalueΔ AA AOR (95%CI)Δ PvalueΔ G A AOR (95%CI)* Pvalue*
Clinical Stage              
III + IV 128 33(25.8) 2.27(1.11 ~ 4.66) 0.025 62(48.4) 1.55(0.87 ~ 2.78) 0.139 33(25.8) - 128(50.0) 128(50.0) 1.86(1.22 ~ 2.82) 0.004
I + II 120 20(16.7) -    55(45.8) -   45(37.5) - 95(39.6) 145(60.4) -  
Tumor differentiation              
Poor 118 29(24.6) 1.34(0.66-2.70) 0.418 52(44.1) 0.89(0.50 ~ 1.58) 0.680 37(31.4) - 110(46.6) 126(53.4) 1.08(0.71 ~ 1.63) 0.729
Well & moderate 130 24(18.5) -   65(50.0) -   41(31.5) - 113(43.5) 147(56.5) -  
Lymph node status              
Positive 111 29(26.1) 2.90 (1.40 ~ 6.03) 0.004 59(53.2) 2.44(1.33-4.50) 0.004 23(20.7) - 117(52.7) 105(47.3) 2.67(1.72 ~ 4.13) 0.001
Negative 137 24(17.5) -   58(42.3) -   55(40.1)   106(38.7) 168(61.3) -  
Serosa invasion              
Positive 126 34(27.0) 2.78(1.34 ~ 5.75) 0.006 62(49.2) 1.74(0.97-3.13) 0.064 30(23.8) - 130(51.6) 122 (48.4) 2.17(1.42 ~ 3.31) 0.001
Negative 122 19(15.6) -   55(45.1)    48(39.3) - 93(38.1) 151 (61.9) -  
  1. Δ, Multivariate logistic regression adjusted by age and gender (genotype AA, AOR = 1.00); *, multivariate logistic regression adjusted by age and gender (A carrier, AOR = 1.00).