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Table 3 Multivariate analysis of factors related to severe thrombocytopenia

From: Factors linked to severe thrombocytopenia during antiviral therapy in patients with chronic hepatitis c and pretreatment low platelet counts

  Multivariate Analysis
Factors Pvalue Odds Ratio 95% Confidence Interval
BMI (< 24.5/≥ 24.5 Kg/m2) 0.280   
ALB (≤ 4.1/> 4.1 g/dL) 0.412   
ALK-p (≥ 97/< 97 U/L) 0.646   
PLT (< 100,000/≥ 100,000/μL) < 0.001 179.219 12.219-2628.602
HCV-RNA (log10, IU/mL) (≥ 5.95/< 5.95) 0.196   
HCV genotype (1/2) 0.419   
Ribavirin dose (≤ 24.58/> 24.58) 0.201   
Rate of PLT decline at week 2 (early PLT decline, > 30%/≤ 30%) 0.003 45.742 3.524-593.689
  1. Abbreviations: ALB: albumin; ALK-p: alkaline phosphatase; AST: aspartate aminotransferase; PLT: platelet; BMI: body mass index; C.I.: confidence interval; HCV: hepatitic C virus.