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Table 2 Genotyping results for ABCB11 c.1331 T > C from patients and controls

From: A frequent variant in the human bile salt export pump gene ABCB11 is associated with hepatitis C virus infection, but not liver stiffness in a German population

ABCB11p.V444A (c.1331 T > C) alleles/genotypes Counts (frequencies) of alleles/genotypes
  Cases (N = 649) Controls (N = 413)
[T] 511 (0.39) 359 (0.43)
[C] 787 (0.61) 467 (0.57)
[TT] 97 (0.15) 82 (0.20)
[TC] 317 (0.49) 195 (0.47)
[CC] 235 (0.36) 136 (0.33)
Tests for association chi 2 P
Allele frequency difference 3.50 0.061
Armitage’s trend test 3.49 0.062
OR statistics OR (95% CI) P
[C] ↔ [T] 1.18 (0.99 - 1.41) 0.061
[CC] ↔ [TT] 1.46 (1.02 - 2.10) 0.040
[CC + CT] ↔ [TT] 1.41 (1.02 - 1.95) 0.037
  1. Patients with HCV infections are regarded as cases.
  2. Abbreviations: A, alanine; ABCB11, ATP-binding cassette, subfamily B, member 11; CI, confidence interval; OR, odds ratio; p, protein (amino acid number), V, valine.