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Figure 4 | BMC Gastroenterology

Figure 4

From: Gastric cancer cell supernatant causes apoptosis and fibrosis in the peritoneal tissues and results in an environment favorable to peritoneal metastases, in vitro and in vivo

Figure 4

Hematoxylin/eosin (H&E) and Masson staining of peritoneum tissues.

Peritoneum tissues from different groups were obtained surgically and subjected to H&E and Masson staining. (A) All photos were obtained at 40 × magnification. Normal peritoneum consists of only a monolayer of mesothelium with little fibrosis (a, d). Peritoneum treated with DMEM also showed small amounts of connective tissue under the mesothelial cells(arrows in b,e). In contrast, peritoneum treated by SF-CM from gastric cancer cells was substantially thickened and contained extensive fibrosis (arrows in c,f). (B) Morphometric parameters of peritoneal tissues. Data are expressed as the mean ± standard error of the mean of at least 3 separate experiments. *P < 0.05.

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BMC Gastroenterology

ISSN: 1471-230X

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