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Table 2 H. pylori sensitivity and specificity depending on the grade of antrum gastritis with atrophy

From: Additional corpus biopsy enhances the detection of Helicobacter pylori infection in a background of gastritis with atrophy

Ca degree of gastritis with atrophy at antrum Normal to mild Moderate to severe
n=164 n=114 n=50
CLOtest Antrum   
 Sensitivity 97.47 (90.31-99.56) 84.00 (63.08-94.75)
 Specificity 100.00 (87.68-100.00) 100.00 (83.42-100.00)
 PPV 100.00 (94.08-100.00) 100.00 (80.76-100.00)
 NPV 94.59 (80.47-99.06) 86.20 (67.43-95.49)
 Accuracy 98.25  
CLOtest Body   
 Sensitivity 100.00 (94.22-100.00) 100.00 (83.42-100.00)
 Specificity 100.00 (87.68-100.00) 100.00 (83.42-100.00)
 PPV 100.00 (94.22-100.00) 100.00 (83.42-100.00)
 NPV 100.00 (87.68-100.00) 100.00 (83.42-100.00)
 Accuracy 100.00 100.00
CLOtest Antrum + Body   
 Sensitivity 100.00 (94.22-100.00) 100.00 (83.42-100.00)
 Specificity 100.00 (87.68-100.00) 100.00 (83.42-100.00)
 PPV 100.00 (94.22-100.00) 100.00 (83.42-100.00)
 NPV 100.00 (87.68-100.00) 100.00 (83.42-100.00)
 Accuracy 100.00 100.00
Histology Antrum   
 Sensitivity 98.73 (92.18-99.93) 84.00 (63.08-94.75)
 Specificity 100.00 (87.68-100.00) 100.00 (83.42-100.00)
 PPV 100.00 (94.15-100.00) 100.00 (80.76-100.00)
 NPV 97.22 (83.80-99.85) 86.20 (67.43-95.49)
 Accuracy 99.12 92.00
Histology Body   
 Sensitivity 100.00 (94.22-100.00) 96.00 (77.68-99.79)
 Specificity 100.00 (87.68-100.00) 100.00 (83.42-100.00)
 PPV 100.00 (94.22-100.00) 100.00 (82.83-100.00)
 NPV 100.00 (87.68-100.00) 96.15 (78.42-99.80)
 Accuracy 100.00 98.00
Histology Antrum + Body   
 Sensitivity 100.00 (94.22-100.00) 96.00 (77.68-99.79)
 Specificity 100.00 (87.68-100.00) 100.00 (83.42-100.00)
 PPV 100.00 (94.22-100.00) 100.00 (82.83-100.00)
 NPV 100.00 (87.68-100.00) 96.15 (78.42-99.80)
 Accuracy 100.00 98.00