Additional corpus biopsy enhances the detection of Helicobacter pylori infection in a background of gastritis with atrophy

Table 2 H. pylori sensitivity and specificity depending on the grade of antrum gastritis with atrophy

Ca degree of gastritis with atrophy at antrum	Normal to mild	Moderate to severe
n=164	n=114	n=50
CLOtest Antrum
Sensitivity	97.47 (90.31-99.56)	84.00 (63.08-94.75)
Specificity	100.00 (87.68-100.00)	100.00 (83.42-100.00)
PPV	100.00 (94.08-100.00)	100.00 (80.76-100.00)
NPV	94.59 (80.47-99.06)	86.20 (67.43-95.49)
Accuracy	98.25
CLOtest Body
Sensitivity	100.00 (94.22-100.00)	100.00 (83.42-100.00)
Specificity	100.00 (87.68-100.00)	100.00 (83.42-100.00)
PPV	100.00 (94.22-100.00)	100.00 (83.42-100.00)
NPV	100.00 (87.68-100.00)	100.00 (83.42-100.00)
Accuracy	100.00	100.00
CLOtest Antrum + Body
Sensitivity	100.00 (94.22-100.00)	100.00 (83.42-100.00)
Specificity	100.00 (87.68-100.00)	100.00 (83.42-100.00)
PPV	100.00 (94.22-100.00)	100.00 (83.42-100.00)
NPV	100.00 (87.68-100.00)	100.00 (83.42-100.00)
Accuracy	100.00	100.00
Histology Antrum
Sensitivity	98.73 (92.18-99.93)	84.00 (63.08-94.75)
Specificity	100.00 (87.68-100.00)	100.00 (83.42-100.00)
PPV	100.00 (94.15-100.00)	100.00 (80.76-100.00)
NPV	97.22 (83.80-99.85)	86.20 (67.43-95.49)
Accuracy	99.12	92.00
Histology Body
Sensitivity	100.00 (94.22-100.00)	96.00 (77.68-99.79)
Specificity	100.00 (87.68-100.00)	100.00 (83.42-100.00)
PPV	100.00 (94.22-100.00)	100.00 (82.83-100.00)
NPV	100.00 (87.68-100.00)	96.15 (78.42-99.80)
Accuracy	100.00	98.00
Histology Antrum + Body
Sensitivity	100.00 (94.22-100.00)	96.00 (77.68-99.79)
Specificity	100.00 (87.68-100.00)	100.00 (83.42-100.00)
PPV	100.00 (94.22-100.00)	100.00 (82.83-100.00)
NPV	100.00 (87.68-100.00)	96.15 (78.42-99.80)
Accuracy	100.00	98.00

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