Table 1 Comparisons in socio-demographic status, co-morbidity and medication between esophageal cancer cases and controls frequency matched by sex, age and index year
From: Risk of esophagus cancer in diabetes mellitus: a population-based case-control study in Taiwan
| Â | Esophageal cancer | Â | |||
|---|---|---|---|---|---|
| Â | No | Yes | Â | ||
| Â | N=2196 | N=549 | Â | ||
|  | n | % | n | % | Pvalue†|
Age, mean (SD), years | 60.9 | (3.03) | 60.9 | (12.9) | 0.24 |
20-39 | 56 | 2.55 | 14 | 2.55 | 1.00 |
40-64 | 1,328 | 60.5 | 332 | 60.5 | Â |
≥65 | 812 | 37.0 | 203 | 37.0 |  |
Sex | Â | Â | Â | Â | 1.00 |
Women | 156 | 7.10 | 39 | 7.10 | Â |
Men | 2,040 | 92.9 | 510 | 92.9 | Â |
Comorbidity | Â | Â | Â | Â | Â |
Diabetes mellitus | 222 | 10.1 | 57 | 10.4 | 0.85 |
Alcoholism | 16 | 0.73 | 53 | 9.65 | <0.0001 |
Obesity | 4 | 0.18 | 1 | 0.18 | 1.00†|
Tobacco use disorder | 7 | 0.32 | 5 | 0.91 | 0.07†|
Periodontal disease | 33 | 1.50 | 2 | 0.36 | 0.03†|
HPV infection | -- | -- | -- | -- | -- |
Hyperlipidemia | 324 | 14.8 | 65 | 11.8 | 0.08 |
Barrett's esophagus | -- | -- | -- | -- | -- |
Esophageal ulcer | 18 | 0.82 | 50 | 9.11 | <0.0001 |
Esophageal reflux | 39 | 1.78 | 43 | 7.83 | <0.0001 |
Medication | Â | Â | Â | Â | Â |
Use of aspirin | 305 | 13.9 | 83 | 15.1 | 0.46 |
Use of COX-2 inhibitors | 495 | 22.5 | 159 | 29.0 | 0.002 |
Use of other NSAIDs | 1,877 | 85.5 | 522 | 95.1 | <0.0001 |