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Table 2 Predictors of IBS with values for IgG and IgG4 food antibodies included in the analyses

From: IgG and IgG4 antibodies in subjects with irritable bowel syndrome: a case control study in the general population

  IgGA IgGB IgG4C
OR (95% CI) p OR (95% CI) p OR (95% CI) p
HSCL101 (1–4) 3.18 (1.82 to 5.55) < 0.001 3.32 (1.88 to 5.86) < 0.001 3.22 (1.84 to 5.62) < 0.001
Muscle skeletal disease (0–12) 1.14 (1.00 to 1.30) 0.051 1.14 (0.99 to 1.31) 0.063 1.14 (1.00 to 1.30) 0.056
Allergic rhinitis (yes/no) 1.73 (0.99 to 3.02) 0.055 1.72 (0.98 to 3.03) 0.060 1.74 (0.99 to 3.05) 0.053
IgG against FP52, mg/L 1.00 (0.99 to 1.01) 0.83     
IgG against FP733, mg/L 1.00 (0.96 to 1.04) 0.97     
IgG against milk, mg/L    1.00 (0.98 to 1.01) 0.54   
IgG against egg, mg/L    1.00 (1.00 to 1.01) 0.62   
IgG against wheat, mg/L    0.99 (0.97 to 1.01) 0.32   
IgG against cod, mg/L    1.08 (0.97 to 1.20) 0.15   
IgG against pork, mg/L    1.04 (0.91 to 1.20) 0.57   
IgG against chicken, mg/L    0.94 (0.87 to 1.02) 0.15   
IgG against beef, mg/L    0.94 (0.78 to 1.14) 0.54   
IgG against brewers’ yeast, mg/L    1.01 (0.97 to 1.04) 0.65   
IgG against Candida albicans, mg/L    1.004 (1.000 to 1.008) 0.051   
IgG4 against milk, mg/L      1.00 (0.98 to 1.02) 0.99
IgG4 against egg, mg/L      0.99 (0.98 to 1.01) 0.43
IgG4 against wheat, mg/L      0.96 (0.91 to 1.02) 0.20
IgG4 against Candida albicans, mg/L      1.56 (0.72 to 3.41) 0.26
Dairy products (portions/day) 0.81 (0.68 to 0.96) 0.014 0.80 (0.68 to 0.95) 0.012 0.81 (0.68 to 0.95) 0.011
Sugar (g/day) 1.01 (1.00 to 1.02) 0.043 1.01 (1.00 to 1.02) 0.049 1.01 (1.00 to 1.02) 0.041
  1. All antibodies and other variables with p < 0.1 are shown. Enter logistic regression.
  2. 1Hopkins Symptom Checklist 10 for mood disorders measurement.
  3. 2food panel with the following allergens; milk, egg, cod, wheat, soybean and peanut.
  4. 3food panel with the following meat allergens; chicken, beef, pork and lamb.
  5. Variables included:
  6. A: age, gender, smoking, number of diseases, allergic rhinitis, HSCL10, muscle skeletal disease, IgG against FP5, IgG against FP73, dairy products, vegetables, potatoes, coffee, tea, water, alcohol, omega 3 fatty acids, sugar.
  7. B: age, gender, smoking, number of diseases, allergic rhinitis, HSCL10, muscle skeletal disease, IgG against milk, IgG against egg, IgG against wheat, IgG against cod, IgG against pork, IgG against chicken, IgG against beef, IgG against brewer’s yeast, IgG against Candida albicans, dairy products, vegetables, potatoes, coffee, tea, water, alcohol, omega 3 fatty acids, sugar.
  8. C: age, gender, smoking, number of diseases, allergic rhinitis, HSCL10, muscle skeletal disease, IgG4 against milk, IgG4 against egg, IgG4 against wheat, IgG4 against Candida albicans, dairy products, vegetables, potatoes, coffee, tea, water, alcohol, omega 3 fatty acids, sugar.