Table 1 Data Among HCV-positive patients who underwent splenectomy (Spx group) and who did not (non-Spx group)
Spx group (n=37) | Non-Spx group (n=90) | P value | |
|---|---|---|---|
Age (y), mean ± SD | 58 ±1 | 61 ± 1 | n.s |
Sex (male / female), n | 19 / 18 | 44 / 46 | n.s |
Body Mass Index (kg/m2), mean ± SD | 24.9 ± 0.5 | 22.7 ± 0.5 | 0.002 |
Hemoglobin level (g/dl), mean ± SD | 12.5 ± 0.3 | 13.2 ± 0.2 | 0.03 |
Platelet count (x104/μl), mean ± SD | 5.9 ± 0.2 | 8.7 ± 0.2 | <0.0001 |
Alanine aminotransferase level (IU/L), mean ± SD | 55 ± 10 | 91 ± 7.9 | 0.001 |
Gamma-glutamyle transpeptidase (IU/L), mean ± SD | 45 ± 7.4 | 60 ± 5.1 | 0.02 |
Albumin level (g/dl), mean ± SD | 3.3 ± 0.07 | 3.9 ± 0.06 | <0.0001 |
Pretreatment viral load (logIU/mL), mean ± SD | 5.9 ± 0.1 | 6.2 ± 0.1 | n.s |
HCV genotype (1/2), n | 32 / 5 | 69 / 21 | n.s |
IL28B genotype (major/minor), n | 26 / 11 | 62 / 28 | n.s |
ITPA genotype (major/minor), n | 26 / 11 | 61 / 29 | n.s |