Table 1 The characteristics of included trials comparing the VSC with the SAC
study, year, country | cecal intubation rate | cecal intubation time | sedation dose | Pain score | ancillary maneuvers | number of patient (n) | colonoscope types | endoscopists' experience level |
|---|---|---|---|---|---|---|---|---|
Akira Horiuchi 2004, Japan | PVSC:95% (117/123) SAC:91% (114/125) P=0.075 | Mean(SD),min PVSC:6.8(5.2) SAC:7.5(4.8) P=0.082 | Mean, Midazolam,mg PVSC:6.5 SAC:7.3 P=0.76 | not stated | Position changes made PVSC:0% SAC:5% P<0.0001 Manual pressure used PVSC:66% SAC:69% P=0.55 | PVSC, small-caliber PVSC, SAC | 374 | Experienced |
Al-Shurieki SH 2005,USA | PVSC:95.8% (115/120) SAC:96.6% (114/118) P=1.0 | Mean(SD),min PVSC:7.8(5.67) SAC:7.9(3.77) P=0.28 | Mean, Meperidine,mg PVSC:56(15) SAC:60(15) P=0.06 Midazolam,mg PVSC:2.2(0.79) SAC:2.5(0.78) P=0.02 | Median patient experience scale PVSC:1 SAC:83% SAC:1 P=0.6 | position change made PVSC:76% P=0.2 manual pressure used PVSC:29% SAC:32% P=0.64 | 238 | PVSC,SAC | Experienced |
Brooker JC 2000,UK | VSC:96.5% (55/57) SAC:90.7 (39/43) P=n.s. | Median(range),min VSC:6min32sec(1 min50sec-19min35sec) SAC:10min35sec(3min45sec-22min35sec) P=0.0005 | Median(range) Pethidine,mg VSC:25(0–75) SCA:37.5(0–100)SCA:1.5(0–2.5) | Median Pain Score rated by patients VSC:7(0–82) SAC:24(0–85) P=0.0081 | not stated | 100 | VSC,SAC | Experienced |
Darlus Sorbi 2001,USA | VSC:100% (25/25) SAC:88% (22/25) P=0.11 | Mean ± SEM VSC:10.6 ± 1.6SAC:10.6 ± 1.7 P=0.97 | Mean ± SEM Meperidine,mg VSC:68 ± 7 SAC:67 ± 5 P=0.68 Midazolam,mg VSC:4.3 ± 0.6 SAC:4.1 ± 0.3 P=0.84 | Mean ± SEM Pain score reported by patients VSC:1.3 ± 0.4 SAC:1.8 ± 0.6 P=0.64 | Mean ± SEM positon changes VSC:0.4 ± 0.1 SAC:1.2 ± 0.4 P=0.46 manual pressure used VSC:0.3 ± 0.1 SAC:1.1 ± 0.4 P=0.05 | 50 | VSC,SAC | limited experienced |
Ichiro Yoshikawa 2002,Japan | experienced VSC:99% (103/104) SAC:98% (101/103) P=n.s. Limited experience VSC:98% (127/129) SAC:95 (125/131) P=n.s. | experienced VSC:9.8 ± 6.6 SAC:10.6 ± 7.2 P=n.s. Limited experience VSC:15.7 ± 9.7 SAC:18.5 ± 12.1 P<0.05 | not stated | Mean(SD) Pain score rated by patients experienced VSC:1.4 ± 1.1 SAC:1.9 ± 1.1 P<0.01 limited experience VSC:1.7 ± 1.0 SAC:2.1 ± 1.2 P<0.01 | Manual pressure used experienced VSC:10% SAC:15% P=n.s. Limited experience VSC:35% SAC:45% P=n.s. | 467 | VSC,SAC | experienced, limited experience |
Lee WH 2007,China | VSC:97% (108/111) SAC:93% (102/110)P=0.28 | Mean ± SD VSC:12.4 ± 6.8 SAC:13.2 ± 11.7 P=0.55 | Mean(SD) Propofol,mg/kg VSC:0.75 ± 0.65 SAC:0.93 ± 0.62 P=0.02 | Mean(SD) Pain score rated by patients VSC:4.6(2.7) SAC:5.9(2.5) P=0.589 | Position change made VSC:23% SAC:34% P=0.01 Manual pressure used VSC:23% SAC:37% P=0.08 | 335 | VSC,SAC | Experienced |
Shumaker DA 2002,USA | PVSC:94.3% (115/122) SAC:89.8% (114/12) P=0.099 | mean(SD) PVSC:9.4(6.8) SAC:7.9(4.5) P=0.089 | Mean(SD) Meperidine,mg PVSC:73(23) SAC:77(25) P=0.168 Fentanyl,mg PVSC:93(35) SAC:93(26) P=0.039 Midazolam,mg PVSC:2.9(1.0) SAC:3.0(1.0) P=0.081 | Mean(SD) Pain score rated by patients PVSC:3.9(3.2) SAC:4.1(3.0) P=0.589 | position change PVSC:33% SAC:33% P=0.96 manual pressure used PVSC:58% SAC:42% P=0.024 | 363 | PVSC,SAC,pediatric colonoscope | Experienced |
Sola-Vera J 2011, Spain | VSC:92.9% (52/56) SAC:90.7% (49/54) P=0.7 | Mean(SD) VSC:6.14(3.5) SAC:7.7(3.8) P=0.035 | Mean(SD) Propofol, mg VSC:155.1 ± 83.3 SAC:176.2 ± 91.2 P=0.2 Fentanyl,mg VSC:0.11 ± 0.03 SAC:0.13 ± 0.04 P=0.06 Midazolam, mg VSC:1.3 ± 0.5 SAC:1.1 ± 0.7 P=0.1 | Mean(SD) Pain rated by patients VSC:2.4 ± 4.8 SAC:2.3 ± 4.4 P=0.9 | Manual pressure used VSC:44.6% SAC:44.4% P=1.0 position change VSC:12.5% SAC:33.3% P=0.012 | 124 | VSC,SAC | Experienced |