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Table 1 Characteristics of the Included Studies

From: Diagnostic accuracy of the aspartate aminotransferase-to-platelet ratio index for the prediction of hepatitis B-related fibrosis: a leading meta-analysis

Author, Year, Country Study/center Description N Interval Between Biopsy & APRI Median/Mean Age, (% male) Etiology Liver Biopsy Description Prevalence Significant Fibrosis (Cirrhosis) QUADAS Score
Chrysanthosa,2006, Greece [31] Retrospective 2 centers 205 same day 51 ± 13(74.6%) HBV ≥ 1.5 cm 42.33%(23.11%) 14
Liu Hongbo,2007, China [33] Retrospective 5 centers 444 ≤ 1 week Training group30(71%) Validation group28(79%) HBV ≥ 1.0 cm 30.18%(4.50%) 14
Giada Sebastiani, 2007, Italy [10] Retrospective 2 centers 110 same day 42.6 ± 11.3(72.7%) HBV ≥ 1.5 cm 68.20%(20%) 14
Beom Kyung Kim 2007, Korea [35] Retrospective 6 centers 346 same time 34 ± 14(85.3%) HBV 4 mm 75.4%(22.8%) 14
W.G. Shin,2008, Korea [32] Retrospective 2 centers 264 same time 24(87.1%) HBV 17 mm 53.4%(3.4%) 14
ChenSheng, Lin 2008, China [34] Retrospective 3 centers 48 Unclear 60.4 ± 11.3(74.2%) HBV Unclear 21.70%(40.20%) 12
Ruidan Zheng, 2008, China [36] Retrospective 3 centers 131 ≤ 1 week 34(84.333%) HBV ≥ 1.0 cm 55.126%(8.897%) 14
Zhongsheng jiang 2008, China [37] Retrospective 1 center 172 ≤ 1 day 35(77.3%) HBV ≥ 1.5 cm 83%(15%) 14
Sheng-Di Wu, 2010, China [7] Retrospective 1 center 78 Unclear 32.6 ± 12.3 (84.6%) HBV ≥ 15 mm 41%(11.5%) 13